A REVIEW ON POST-PARTUM DEPRESSION
Dr. Satish S.* and Aiswarya T. V.
Abstract
Postpartum depression (PPD) is a devastating mental disorder affecting
10-20% of new mothers. Psychiatric disorders always go unnoticed,
even with the high prevalence. This review summarizes the
variousanticipated pathophysiological mechanisms contributory to
PPD, by highlighting clinical and basic science research findings.
Additionally, the review discussed the risk factors, management,
treatment, and biomarkers of PPD. This study aimed to review the
related study on PPD and provide a current update on the concept,
treatment, and future perspective. The extensive literature search was
carried out using major search engines like PubMed, Embase, and Scopus using the Boolean
operators. ProQuest, in the period 2012-2022, published articles with keywords post-partum
depression, risk factors, treatment, pathophysiology, biomarkers, and management. Data
generated from this current review can be used for developing a screening tool and a
preventative program for high-risk pregnant women. The PPD mechanism study provides
insight into the development of early diagnosis and treatment of the condition. The update on
the PPD offers researchersthe voids that need to be filled in the area of diagnosis and
management of the condition The current review provides an update on PPD. It also
recommends prioritizing mental health care and carrying out more studies on the early
identification of risk for the development of PPD. It is anticipated that emerging knowledge
on pathophysiology and risk factors will lead to the developmentof new treatments for PPD.
Keywords: Post-partum depression, Risk factors, Psychiatric disorder, Treatment, Management.
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