Abstract

A REVIEW ON ANIMAL STUDIES IN DRUG DEVELOPMENT

Aswathi Nambiar M. P.*, Ummu Aleema M. K. and Thasneem Abdullakunhi

Abstract

Drug discovery is the process by which new candidate medications are discovered. The purpose of animal studies is to verify the pharmacologic activity of the new drug, identify any unexpected pharmacologic activity and develop initial data based on the action of the drug in vivo. Institutional Animals Ethics Committee means a body comprising of a group of persons recognized and registered by the Committee for the purpose of control and supervision of experiments on animals performed in an establishment which is constituted and operated in accordance with procedures specified for the purpose by the Committee. Anesthesia is the use of medicines to prevent pain during surgery and other procedures. Euthanasia it is the state causes death without pain. Skeletal muscle relaxants are used to treat conditions associated with hyper excitable skeletal muscle—specifically, spasticity and muscle spasms. Anxiolytics are agents prescribed to treat and prevent symptoms of anxiety or for the management of anxiety disorders.

Keywords: Drug discovery, pre-clinical and clinical research, animal experimentation in drug development, IAEC, CPCSEA, skeletal muscle relaxants, anxiolytics.