Abstract

A REVIEW ON: TRANSDERMAL PATCHES

Shubham Warke*

Abstract

For heaps of years, human civilizations have carried out substances to the skin as beauty and medicinal agents. however, it was not till the 20th century that the skin came for use as a drug delivery route. In reality, Merriam Webster dates the word “transdermal” to 1944 highlighting that it is a especially current idea in medical and pharmaceutical practices. Transdermal preparation is self‐ contained, discrete dosage form. Drug transport through the skin to acquire a systemic effect without generating any fluctuations in plasma concentration of the drug. Topical administration of therapeutic agents gives many benefits over conventional oral and invasive strategies of drug delivery. And offer managed release of the drug for extended duration of the time. This review article covers brief outline advantages, skin pathways for transdermal drug delivery systems (TDDS), various components of transdermal patch, and techniques for preparations of transdermal patches, evaluation of transdermal system, general clinical consideration in the use of TDDS and difficulty of TDDS.

Keywords: Transdermal, Drug shipping, Matrix, Reservoir, Permeation pathways.