Abstract

A CONCISE REVIEW ON HERBAL INGREDIENTS OF TRADITIONAL SIDDHA POLYHERBAL FORMULATION “THETRAN VIDHAI KUDINEER” FOR ANTIDIABETIC EFFICACY

Dr. Geetha Thambiraj*

Abstract

Diabetes mellitus is a common complaint in day-to-day general practice. The chronicity and uncontrolled high blood glucose lead to vascular complications either microvascular or macrovascular pathology such as neuropathy, retinopathy, nephropathy and other cardiovascular disorders. Hence rigorous measures need to be taken to control hyperglycemia. Since there is an increased curiosity towards herbal medicine due to its less adverse effects, research needs to be conducted on the antidiabetic efficacy of the existing plants. This review is about the herbal ingredients of a polyherbal formulation, “Thetran Vidhai Kudineer” presented in the classical textbook of Siddha Materia Medica which is indicated for hyperglycemia. The herbal ingredients mentioned in the literature are Cassia auriculata, Strychnos potatorum seeds, Terminalia chebula, Limonia acidissimia resin. The search for the review was done on databases like Google scholar, Pubmed, and Science Direct to retrieve the information on preclinical studies conducted on the herbal ingredients of Thetran Vidhai kudineer. Overall 15 preclinical studies were reviewed, and the results were presented. Also, the mechanism of action behind the antidiabetic activity of these herbs were discussed. This review could bring new insights to approach the Siddha formulation of medicine in a scientific way to prove its efficacy and pharmacological actions of the natural plants.

Keywords: Antidiabetic, Diabetes mellitus, Polyherbal formulation, Thetran vidhai kudineer.