Abstract

AN OPEN LABELED, SINGLE ARM, CLINICAL STUDY TO EVALUATE EFFICACY AND SAFETY OF GRACE HING (HING OIL 15 MG) HPMC CAPSULES IN THE TREATMENT OF ABDOMINAL PAIN AND FUNCTIONAL DYSPEPSIA

Baburao Vikram*, Blen Amare and Sunil Gupta

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Abstract

Background and Aim: Abdominal pain should be major complaint and reason for consultation in medical aid. It affects nearly every person once in their lifetime regardless of age, gender and social background. Abdominal pain can be caused by a broad spectrum of diseases from incidental and self-limited (e.g. gastroenteritis) to acute and serious conditions (e.g. abdominal aortic aneurysm). Management of this problem has continuously been a challenge due to the adverse event and the cost related to the chemical drugs. Man since time immemorial has been using herbs or plant products as medicine for developing immunity or resistance against cold, coryza, joint pains, and fever. The aim of this study is to demonstrate the safety and efficacy of hing oil for abdominal pain and functional dyspepsia patients. Material and Method: The present open labeled, single arm, study on 15 subjects characterized with functional dyspepsia and associated abdominal pain demonstrated the safety and efficacy of hing oil. The primary end point was a decrease in VAS for pain intensity. While the secondary end points include efficacy assessment of Nepean Dyspepsia Index (NDI), Gastrointestinal Symptom Rating Scale (GSRS), Global overall symptom scale(GOS), and adverse events. Result and Conclusion: These finding indicate that GRACE HING (Hing oil 15 mg) HPMC Capsules improved patients’ standard of living with high interest and focus on their daily routines after taking the capsules because of an advance improvement in bloating, postprandial fullness, food intake, heart burn, constipation, and digestion with no side effects or adverse events.

Keywords: GOS, GSRS, Hing Oil, Medicinal Plant, NDI, Treatment.