Abstract

APOPTOSIS

Aasawaree Vaibhav Mane*, Vishakha Prabhakar Patil and Dr. Rupali Rajesh Tasgaonkar

Abstract

Apoptosis is a form of cell death that occurs when a cascade of molecular events in a cell causes it to die. The process of planned cell death, which occurs on a regular basis to maintain a homeostatic balance between the rates of cell production and cellular damage. Apoptosis is distinguished by different phenotypic traits and an energy-dependent metabolic process. This review focuses on the primary apoptotic signaling pathways as well as the molecular components engaged. Defects can develop at any point along these pathways, resulting in malignant transformation of the afflicted cell, tumor spread, and medication tolerance.

Keywords: Apoptosis, Programmed Cell Death, Extrinsic and Intrinsic Pathway.