Abstract

A CRITICAL STUDY IN STANDARDIZATION OF AAMA AND KLEDA IN RELATION TO INFLAMMATORY MARKERS

Dr. Hrishita S. Dahilekar M.D. Ph.D. (S), *Dr. Hemant Toshikhane, Dean and Dr. Sandeep G. Dahilekar M.D. Ph.D. (S)

Abstract

According to modern, the Inflammatory process plays an important role in the disease's development and degree of severity. These inflammatory processes are laboratically identified by an increase in the values of Inflammatory markers. ESR and CRP are widely used as diagnostic Inflammatory markers. These are categorized under Positive acute phase reactants and are generally suitable as a prognosis indicator of the disease. These Inflammatory markers are further divided as Acute or Chronic Inflammatory markers according to the duration of the manifestation. According to Ayurved impaired Agni at Jatharagni and Dhatwagni level is responsible for the development of Samata in the Vyadhi. The severity of Samata can be measured by the involvement of doshas, dushyas, and the duration of clinical manifestation of Dosha Samata such as Dosha- Samata and Rasa-Samata. The prognosis and line of treatment of vyadhi are based on the type of Samata, Doshapaka, and Dhatupaka Lakshana. Ultimately all these are related to the presence and absence of Aama and Kleda as pathogenetic factors. Hence „Ama‟ and „Kleda‟ plays an important role as Diagnostic and Prognostic markers of the Vyadhi. In this paper, the conceptual study of “Samata” is presented in terms of entities like Aam and Kleda and their correlation with inflammatory markers in ESR and CRP respectively.

Keywords: Inflammation, Inflammatory markers, Acute phase Reactant, ESR, CRP, Aama, Kleda, Vyadhi Samata, Doshapaka, Dhatupaka.