Abstract

IN - VITRO ANTIBACTERIAL ACTIVITY OF ETHANOLIC EXTRACTS OF VIOLA SERPENS AND MORUS NIGRA AGAINST PATHOGENS ISOLATED FROM PATIENTS SUFFERING FROM JAUNDICE

Anu Kumar*, Manisha Kumari, Rita Singh Mazumdar and Tejpal Dhewa

Abstract

In the present scenario there is an urgent need to discover new antimicrobial agents for therapeutic use, as resistance to current drugs increase in severity and extent on the passage of time. Our research work was focused on the identification of natural products from leaves extracts of Morus nigra and Viola serpens in order to decipher the antibacterial activity against bacteria causing jaundice disease. Natural products based drugs are known as potential pharmacological agents. The Phytochemical screening of the plants studied showed the presence of Flavonoids, Terpenoids, reducing sugars, amino acids and tannins. In-vitro antibacterial activity was evaluated against strains isolated from patients suffering from jaundice i.e. Staphylococcus aureus, Pseudomonas aeruginosas, Salmonella typhi, Escherichia coli and Klebsiella pneumonia. Comparative study of Ethanolic extract of Viola serpens & Morus nigrawith standard antibiotics showed that Ethanolic extract of Viola serpens showed maximum antibacterial activity. Concerning the zone of inhibition, the values were merely higher for those caused by the plant extracts as compared to different antibiotics.

Keywords: Medicinal plants, Antibacterial activity and Phytochemical, Antibiogram.