RETROSPECTIVE ANALYSIS OF HOSPITAL ADMISSIONS DUE TO CUTANEOUS ADVERSE DRUG REACTIONS IN A TERTIARY CARE CENTER
C. Vasanthi, Anish Stephen, Darling Chellathai, J.Damodaran, S.Anandan
Abstract
Background and Objective: Adverse drug reactions are a constraint to
successful outcome of Pharmacotherapy. ADRs can result in serious
implications like Morbidity & Mortality which in most of the cases can
be prevented. ADRs are considered a potential burden from the
pharmacoeconomics perspective. This study analyses the Hospital
admissions due to ADRs Methods: This is a retrospective study which
analyzes the admissions of ADRs as the chief presenting symptoms in
Sri Ramachandra medical college & hospital in the time period of 9
years (year 2004 to year 2012). In the Span of 9 years 42 cases which
comprised of 31females and 11 males were admitted with a wide
spectrum of presenting symptoms which pointed out to be ADRs.
Results: Among the admitted cases the presenting symptoms which
indicated ADRs were Generalized Maculopapular rash, generalized reddish scaly lesion
Angioedema, urticaria and Pityriasis Rosacea. The drugs were found out to be combinations
of NSAIDs with Antiepileptic, Combination of NSAIDs with Antibiotics and Antiepileptics
alone sharing the top spot of causative agents , other agents being antipsychotics , hormones ,
retinoid , Antibiotics , NSAIDs , Antitubercular drugs , Herbal agents.
Keywords: ADRs – adverse drug reactions.
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