Abstract

RETROSPECTIVE ANALYSIS OF HOSPITAL ADMISSIONS DUE TO CUTANEOUS ADVERSE DRUG REACTIONS IN A TERTIARY CARE CENTER

C. Vasanthi, Anish Stephen, Darling Chellathai, J.Damodaran, S.Anandan

Abstract

Background and Objective: Adverse drug reactions are a constraint to successful outcome of Pharmacotherapy. ADRs can result in serious implications like Morbidity & Mortality which in most of the cases can be prevented. ADRs are considered a potential burden from the pharmacoeconomics perspective. This study analyses the Hospital admissions due to ADRs Methods: This is a retrospective study which analyzes the admissions of ADRs as the chief presenting symptoms in Sri Ramachandra medical college & hospital in the time period of 9 years (year 2004 to year 2012). In the Span of 9 years 42 cases which comprised of 31females and 11 males were admitted with a wide spectrum of presenting symptoms which pointed out to be ADRs. Results: Among the admitted cases the presenting symptoms which indicated ADRs were Generalized Maculopapular rash, generalized reddish scaly lesion Angioedema, urticaria and Pityriasis Rosacea. The drugs were found out to be combinations of NSAIDs with Antiepileptic, Combination of NSAIDs with Antibiotics and Antiepileptics alone sharing the top spot of causative agents , other agents being antipsychotics , hormones , retinoid , Antibiotics , NSAIDs , Antitubercular drugs , Herbal agents.

Keywords: ADRs – adverse drug reactions.