Abstract

BRIEF OVERVIEW: THE FUNDAMENTALS OF FORMULATING AND EVALUATING CHEWABLE TABLETS WITH A BITTER MASKED TEST

Ajim A. Shaikh*, Dr. C. V. Panchal, P. H. Shaikh, Sumit S. Sontakke and Mahin Shaikh

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Abstract

Tablets that can be eaten between the teeth must be broken before consumption. These tablets are provided to individuals who detest swallowing and to youngsters who have trouble swallowing. Whether or not they are really chewed, typically chewable tablets dissolve smoothly, taste good, and leave no bitter or off-putting aftertaste. Patients who need easy-to-swallow dosage forms, like chewable pills, the most include elderly and paediatric patients, as well as patients travelling who might not have ready access to water. The gum core of a chewable tablet, which may or may not be coated, makes up its composition. Insoluble gum base, fillers, waxes, antioxidants, sweeteners, and flavourings make up the core. Depending on the base utilised and its characteristics, the percentage of gum base ranges from 30 to 60%. To make it more appetising, a flavouring agent is added. The composition of chewable pills takes into account a number of variables. Organoleptic qualities of the active medicinal ingredients are the main focus here, but other formulation parameters like flow, lubrication, disintegration, organoleptic features, compressibility, compatibility, and stability also play a vital role. To create a formula and process combination that yields a product with good organoleptic qualities, a formulator may employ one or more methods. The flow, compressibility, and stability properties of this substance must be satisfactory.

Keywords: Gum core, compressibility, chewable tablet, antioxidant, etc.