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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL STUDIES OF 7-ETHYL-2, 4-BIS(4-METHOXY-PHENYL)-3-AZABICYCLO[ 3.3.1]NONAN-9-ONE

S. Mohamed Rabeek, M. Seeni Mubarak*, H.Mohamed Kasim Seit, R. Kathirvel, M. Sathyanarayanan

Abstract

The newly synthesized 7-ethyl-2,4-bis(4-methoxy-phenyl)-3-azabicyclo[ 3.3.1]nonan-9-one. The compound has been derived by the condensation of 4-ethylcyclohexanone and 4-methoxybenzaldehyde using ammonium formate. The structure of the synthesized compound was elucidated by spectral studies such as IR, 1H, 13C NMR and elemental analysis. The newly synthesized compound was screened for its antimicrobial activity against staphylococcus aureus, escherichiacoli, pseudomonas aerugionosa, aspergillusnigar and mucor.

Keywords: 4-ethylcyclohexanone, 4-methoxybenzaldehyde, Spectral studies, Antimicrobial activity.

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