Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL ANALYSIS OF KANTAKARYADI KASHAYA- FOR BEEJAKOSHA GRANTHI (OVARIAN CYST)

Dr. Tejal Prajapati*, Dr. Nilesh Prajapati and Dr. Nisha Khorajiya

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Abstract

Kantakaryadi Kashaya is a polyherbal formulation containing various Ayurvedic medicinal drugs and is mentioned in Sahastra yoga. Sahastra Yoga has Cleary mentioned Kantakari, Varuna, Agnimantha, Shigru, Shunthi, Punarnava Siddha Kashayain context of Antarvidradhi. Granthi and Vidradhi having similar Dushya like Mamsa, Asruk, and Meda. So, line of treatment Vidradhi and Granthi can be same. Ovarian cyst thought mostly benign pose a diagnostic dilemma to the gynaecologist as well as to the pathologist. Ovarian cyst is an emerging problem among the women of reproductive age group. Ovarian cysts are seen in all age groups and are subdivided in physiological and pathological cysts.[1] Kantakaryadi Kashaya can be a promising formulation in the management of ovarian cyst. In the present study, an attempt has been made to develop pharmacognostical and pharmaceutical standards for Kantakaryadi Kashaya. For assurance of quality of herbal compounds pharmacognostical and pharmaceutical analysis should be done. Methods: Kantakaryadi Kashaya was subjected to microscopic evaluation for pharmacognostical study, physic-chemical analysis like hardness, weight variation, and loss on drying, ash value, acid insoluble extract, pH value, water soluble extract, alcohol soluble extract, and high-Performance thin layer chromatography (HPTLC). Results: Pharmacognostical study showed the presence of certain identifying characters of all of the ingredients of that is KANTAKARYADI KASHAYA is Kantkari, Agnimanth Varun, Shunthi, Punarnava, Shigru. In pharmaceutical study, preliminary physico-chemical analysis showed that, ash value 09.30%w/w, loss on drying 8.40%w/w, water soluble extract 11.3%w/w, alcohol soluble extract 04.00%w/w. HPTLC analysis showed nine spots in 254nm and seven spots in 366nm. Conclusion: Present work was carried out to standardize the polyherbal formulation Kantakaryadi Kashaya in terms of its identity, quality and purity. Pharmacognostical and physico-chemical observations revealed the specific characters of all active constituents in the preparation.

Keywords: Kantakaryadi kashaya, Pharmacognocy, Pharmaceutics, overian cyst.