Abstract

PHYTOCHEMICAL SCREENING AND INVITRO ANTIHELMINTIC ACTIVITY OF METHANOLIC EXTRACT OF DAUCUS CAROTA LINN.

Gadala Sabari*, Dr. T. Satyanarayana, Sk. Maneesha, T. Raj Kumar, P. Mounika, Sk. Nafeesha and B. Susmithanjana

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Abstract

Development of anthelmintic resistance and high cost of conventional anthelmintic drugs led to the evaluation of medicinal plants as a alternative source of anthelmintics. In the present study, the roots of Daucus Carota were successively extracted with maceration using methanol as a solvent. The aim of the present study was to perform the phytochemical screening and to evaluate the anthelmintic activity of methanolic extract of roots of Daucus Carota belonging to the family Apiaceae. The anthelmintic activity was analyzed by methanolic extract of different concentrations-25,50,100mg/ml by using Indian adult earthworm, Pheretima posthuma having anatomical and physiological resemblance with intestinal worms. The time of paralysis and time of death were studied and the activity was compared with Piperazine citrate as a standad reference. We demonstrated that, the results supported the traditional use of Daucus Carota in the treatment of Helminthiasis.

Keywords: Daucus Carota roots, phytochemical screening, pheretima posthuma, piperazine citrate.