Abstract

NANOCOCHLEATES: A NOVEL DRUG DELIVERY APPROACH

Chaitany Kumawat, Kanika Singh Sunil Kumar*, Khanderao Jadhav, Rishikesh Bachhav

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Abstract

An innovative drug delivery system called as nanocochleate allows the systemic and oral distribution of different charged drug molecules into a multilayered structure that contains a solid-lipid bilayer in the form of a sheet that has been rolled up spirally. The nanocochleate structure shields the enclosed molecules from the hostile environment. Drugs that are hydrophobic, positively charged, negatively charged, and have poor oral absorption can be encapsulated by nanocochleate. Creating nanocochleates and using them to deliver a wide range of active ingredients for various uses. Because nanocochleates have far fewer restrictions than conventional dosage forms and delivery systems, they are more effective. Expands in scope and promise as a medication delivery mechanism.

Keywords: Nanocochleates, Bilayers, Phosphatidyl serine, Liposomes, Phospholipids.