WJPR Citation New

  All Since 2019
 Citation  7475  4312
 h-index  28  21
 i10-index  197  83

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
Download Article: Click Here

Search

Track Your Article

Abstract

VOLUMETRIC AND ULTRAACOUSTIC APPROACH TO INTERACTION OF SODIUM SALICYLATE AND 4- AMINOANTIPYRINE DRUGS IN AQUEOUS GLYCINE/L-PROLINE SOLUTION AT DIFFERENT TEMPERATURES

R. T. Sawale*, S. S. Tiwade, D. B. Kadam and A. D. Arsule

.

Abstract

Major drugs are small organic molecules with the purpose to inhibit and activate the function of biomolecules such as lipids, carbohydrates and proteins. Drug design and development process involves the design of molecules to facilitate the drug mechanism and their action. Studies of thermophysical and biological properties play a vital role to understand the pattern of molecular interactions of drug with the biomolecules. Present article, reports the density, ultrasonic velocity and refractive index of sodium salicylate and 4-aminoantipyrine in aqueous solution of glycine/L-proline at T = (303.15, 308.15 and 313.15) K and atmospheric pressure. Apparent molar properties such as apparent molar volume ( 2, V ) and apparent molar compressibility (   S,2, ) have been calculated from , u and n data. The standard partial molar volumes ( o V 2, ) and compressibilities ( 0 ,2,  S ) of solute in aqueous glycine/L-proline solution have also been obtained by extrapolating the plots. These properties have been interpreted in terms of hydration behaviour and solute-solute/solute-solvent interactions of sodium salicylate and 4- aminoantipyrine drugs in studied solution.

Keywords: Molecular interaction, NSAID, Amino acid, Aqueous solution, Thermodynamic properties.


[Full Text Article]  [Download Certificate]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More