STERIOCHEMICAL ASSIGNMENT OF ALCOHOLS –A VERSATILE CHIRAL BUILDING BLOCKS STUDIES TOWARDS TOTAL SYNTHESIS OF (-)-AUREONETOL
Govind Jadhav, Prasad Kadam, Ganpat Nagargoje, Abhay Bondge, Shital Jadhav,
Vijaykumar More
Abstract
A novel and interesting synthetic strategies. However, there is enough
scope to develop a more efficient synthetic approach for the synthesis
of (-) -Aureonetol. Wittig olefination of the aldehydes or ketones to get
allyl vinyl ethers followed by a Claisen rearrangement for the
generation of 4-pentenal. This method has been extensively studied
and applied to the synthesis of (-) –Aureonetol.
Keywords: Dicyclohexylidene protection, Oxidative cleavage, Wittig reaction and Claisen rearrangement.
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