Abstract

AN OVERVIEW OF TRANSDERMAL DRUG DELIVERY SYSTEM

T. Pradeepa* and J. Aruna

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Abstract

Today about 74% of drugs are taken orally and are found not to be as effective as desired. To improve such characters transdermal drug delivery system was emerged. Drug delivery through the skin to achieve a systemic effect of a drug is commonly known as transdermal drug delivery and differs from traditional topical drug delivery. TDDS are of many types varying from single layer drug in adhesive to multi layer drug in adhesive and others are reservoir and the matrix systems. Various factors are involved, both of skin and drug, which affects the availability of drug in the systemic circulation through the transdermal route and are essential to be considered during designing of the system.

Keywords: Transdermal drug delivery system, patches, skin permeation, evaluation.