Abstract

NANOCELLULAR DRUG DELIVERY SYSTEMS FOR IMPROVING THE EFFICACY AND SAFETY OF ANTIHYPERTENSIVE DRUGS

Astha*, Prof. Dr. Pranav Kumar Upadhyay

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Abstract

This review article explores the potential of nanocellular drug delivery systems for improving the efficacy and safety of antihypertensive drugs. The article provides a detailed discussion of the limitations of conventional drug delivery systems, including poor bioavailability, lack of targeting, and limited therapeutic index. It also discusses the mechanisms of action of nanocellular drug delivery systems, which utilize nanosized carriers to improve drug delivery to specific tissues and cells. The article delves into the potential advantages of nanocellular drug delivery systems, including improved bioavailability due to increased solubility and permeability, enhanced targeting through surface modification and ligand-based approaches, and the potential for improved therapeutic index by reducing off-target effects and increasing drug concentrations at the site of action. Finally, the article discusses the challenges and future directions for this technology, including the need for standardized manufacturing processes, improved targeting strategies, and the need for more clinical trials. Despite these challenges, the potential of nanocellular drug delivery systems for revolutionizing the treatment of hypertension and other cardiovascular diseases is clear. Overall, this article provides a comprehensive overview of the potential of nanocellular drug delivery systems for improving the treatment of hypertension and other cardiovascular diseases. It highlights the advantages of this technology and the promising results of preclinical and clinical studies, while also discussing the challenges and future directions for this field.

Keywords: Nanocellular, antihypertensive, nanosized carriers, cardiovascular diseases. Introduction to Hypertension and Antihypertensive Drugs.