Abstract

ANALYSIS OF PASSION FRUIT (EXTRACT PROTOCATECHUIC ACID) AS AN ANTIOXIDANT OF NUCLEIC ACIDS IN THE HUMAN BODY

Danna María Arzeta-Sanabria, Alison Stefany Corona-Hernández, Guadalupe Herrera-Oceguera, Alejandra Tirado-Calderón and *Manuel González-Pérez

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Abstract

Passion fruit (Passiflora edulis f. flavicarpa) is a potential source of phytochemical compounds with anti-proliferative properties. It is established as an approximation to the biotechnological application for this species. This investigation aimed to analyze one of the passion fruit components Protocatechuic Acid (PCA), as an antioxidant of nucleic acids in the human organism. Quantum chemistry uses hyperchem software. SE-PM3 method and Polak Reviere. It was calculated the Electron Transfer coefficient (ETC) that consists of calculating the HOMO and LUMO of a molecule in question. Then get the forbidden band (Bg). This Bg is calculated as the absolute value of the HOMO-LUMO difference. The electrostatic potential is calculated by subtracting and obtaining the absolute value of the electron densities of the molecules. The obtained value of the ETC is divided between the difference of the electronic densities or electrostatic potential. It was found that PCA is a non-prolonged-acting substance; that is, it takes a very short time inside the body. We demonstrated in silico that PCA has many health benefits, as the researchers we cited in the references reported. We found and verified that PCA is a chemically related and potent antioxidant of the BNs of DNA and RNA nucleic acids.

Keywords: Passion fruit, Protocatechuic acid, Antioxidant, Amino acids, Nucleic acid, Human Body.