Abstract

HAIR GROWTH STIMULATING EFFECT AND PHYTOCHEMICAL EVALUATION HYDOALCOHOLIC EXTRACT OF CARICA PAPAYA LEAVES

Indu Dangi*, Manoj Sahu, Dr. Lokesh Verma, Dr. Jitendra Banweer

.

Abstract

Alopecia is a widespread issue that may negatively impact both genders' physiological health and sense of self. The pharmacological benefits of synthetic drugs are restricted by their adverse effects; as a result, natural medicines with added benefits are preferred over synthetic ones. Carica papaya is medicinal plant with numerous health benefits. This study aims at determining effect of Carica papaya extract on hair problems. The plant material was collected & subjected to hydroalcoholic extraction. Further qualitative & quantitative studies were undertaken. Also, various parameters for checking its effectiveness were tested on experimental animals. Results revealed that extract contain carbohydrate, protein, saponin, flavonoid, Tannin & phenolics. Also, the total phenol & flavonoid content was found to be 0.241 & 0.763 mg/100mg. Qualitative studies on hair growth point towards fact that for Carica papaya (5% ointment) is capable of initiating & completing hair growth in very short duration which is even less than standard. Further the percentage of hair follicle was found to be highest which is 233.3 ± 1.2 at 30 days for Hydroalcoholic extract of Carica papaya (5% ointment). In case of hair length, extract of Carica papaya (5% ointment) resulted in hair length of 4.05±0.39mm with only slight difference compared to the standard. From these results it can be assumed that hydroalcoholic extract of Carica papya can help in inhibiting hair loss & regrow the hairs. Further clinical studies are required to manufacture formulation containing this extract.

Keywords: Hair loss, Alopecia, Herbal medicines, Phytochemicals, Carica papaya, Minoxidil, Finasteride.