Abstract

A REVIEW: NANOPARTICLES LOADED DRUG DELIVERY SYSTEM USING NATURAL POLYMER

Shradha Sahu*, Vishal Singh, Rajeev Shukla and Aditya Gupta

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Abstract

Nanoparticles can be defined as colloidal particles. Nanoparticles are the basic components of Nano technology. The nanoparticles range in size from 1 to 100 nm and are composed of metal, metal oxides, organic material and carbon. Nanoparticles come in different sizes, shapes and sizes regardless of the material they are made of. The surface may be irregular with surface variations or uniform. The advantage of nanotechnology is the delivery of safe and effective medicines (nanomedicine) with a significant impact on the pharmaceutical and biotech industry landscape. Nanomedicine is a broad field and includes nanoparticles acting as biological mimics (e.g. functionalized carbon nanotubes), “nanomacha” (e.g. those made up of interchangeable pieces of DNA, and DNA -scaffolds such as the octahedron and the cube) and nanofibers and polymers nanostructures as biomaterials ,shape memory polymers such as molecular switches, and devices based on nanoscale microfabrication, sensors, and laboratory diagnostics.The prefix “nano” has found in last decade an ever-increasing application to different fields of the knowledge. Inflammation is generally defined as a response to stimulation by invading pathogens or endogenous signals such as damaged cells that results in tissue repair or sometimes pathology, when the response goes unchecked. Active ingredient and excipients are two main ingredients of any pharmaceutical formulation. This paper presents a review on Nanoparticles their types, properties, synthesis methods and its applications.

Keywords: Nanoparticles, Drug delivery, Collagen, Inflammatory disease, Treatment.