Abstract

PHYTOCHEMICAL AND PHYTOPHARMACOLOGICAL WOMB OF CELASTRUS PANICULATUS WILD.: AN OVERVIEW SINCE 1962-2021

Birapaku Monika, Pabbathi Jacob Doss* and Chintha Venkataramaiah

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Abstract

The multi-purpose medicinal plant, Celastrus paniculatus is widely used for a number of medicinal activities worldwide either as crude extracts or as pure compounds since the times unknown. This plant has proved for multiple pharmacological activities including cognition enhancing, neuroprotective, antipsychotic, anti-depressant, antibacterial, anti-arthritic, antimalarial, analgesic, anti-inflammatory, anti-fertility, cardiovascular, locomotor, anxiolytic, wound healing activity, anti-spasmodic, hypolipidemic, anti-cancerous, antioxidant and ironchelating activity with different extract as well as various phytoconstituents such as monoterpenes, sesquiterpenes esters, diterpenoids, triterpenoids, alkaloids, fatty acids, steroids, flavonoids, polyol, epoxides, polysaccharides and vitamin C of the plant. Instead of searching for new bioactive compounds of medicinal plant origin continuously, it would be always better and time saving process to re-define the usage of bioactive scaffolds of multipurpose medicinal plant like Celastrus paniculatus against different human ailments. It indirectly states that usage of existing activity-biased phytoconstituents will also save billions of dollars’ worth due to their chemical diversity and bioavailability. By keeping in view of relative importance of this plant, discussion has made in-detail on the reported phytochemistry, ethnopharmacological and phytopharmacological activities of C. paniculatus since 1962-2021.

Keywords: Celastrus paniculatus, Phytoconstituents, Ethno/Phytopharmacological activities.