Abstract

ANTIMICROBIAL AND PHYTOCHEMICAL SCREENING OF CORDIA AFRICANA IN SUDAN

Emtinan A. Alhadi*, Hassan. S. Khalid, Muddathir. S. Alhassan, Ahmed S. Kabbashi and Mohammed O. Noor

Abstract

The present study was conducted to investigate the antimicrobial activity and phytochemical screening for different parts (leaves, stem, park and fruit) of Cordia africana. The extracts of C. africana was screened for its antimicrobial activity against four standard bacteria, two Gram-positive bacterial strains (Bacillus subtilis and Staphylococcus aureus), two Gram-negative bacterial strains (Escherichia coli and Pseudomonas aeruginosa) and two fungal strains (Apergillus niger and Candida albicans) using the cup plate agar diffusion method. The methanol extract of C. Africana extracts exhibited inhibitory effects against most of the tested organisms with zone of inhibition ranging from (11-30 mm). Phytochemical investigation for the methanolic extracts showed the presences of cumarins, saponins, sterols and triterpens, while anthraquienones glycosides, alkaloids and cyanogenic glycosides were absenced. In conclusion: These studies conducted for both C. africana in the treatment of bacterial and fungal in vitro.

Keywords: In vitro, antimicrobial activity, phytochemical screening, C. Africana, in Sudan.