Abstract

A COMPARATIVE STUDY ON ANTIBACTERIAL ACTIVITY OF ANDROGRAPHIS PANICULATA DIFFERENT BARK EXTRACTS AGAINST SOME HUMAN PATHOGENIC BACTERIA’S

*Priyanka Pandey and Wasim Raja

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Abstract

The use of plant extracts for antimicrobial activity and other diseases have been observed to be promising remedies since ancient time in Chinese medicine, Ayurveda, Arabic, and Unani medicine. The plants have traditionally furnish a source of hope for novel drug compounds, as plant herbal mixtures have made large endowment to human health and well being. The use of plant extracts with known antimicrobial properties can be of appreciable significance for therapeutic treatment. Presently, the research has been initiated to study the antibacterial activity of chloroform, and methanol extracts of Andrographis paniculata to emphasize the potential of herbal components in the field of medical science to kill various dreadful pathogens. The agar well diffusion method was followed to evaluate the antibacterial activity of leaf and stem extracts of A. paniculata against Bacillus subtilis, S. aureus, Enterococcus, P. aeruginosa, K. pneumonia and E. coli. The result revealed that all the doses of both extracts of A. paniculata potentially inhibited the growth of all the pathogens tested. Hence, the present investigation evaluates the potential anti bacterial activity of methanol extract of leaf and stem extract of A. paniculata.

Keywords: Andrographis paniculata, antimicrobial activity, pathogens, methanol, root stem bark extract.