Abstract

A COMPARISON OF THE ANTI-PSEUDOMONAS ACTIVITY OF RED PIPER BETEL LEAF EXTRACT (PIPER CROCATUM RUIZ & PAV) AND JATROPHA (JATROPHA CURCAS L.) LEAVES

Sri Agung Fitri Kusuma*, Irma Erika H. and Danni Ramdhani

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Abstract

Objective: This study we aimed to compare the antibacterial activity of red piper betel leaf extract (Piper crocatum Ruiz & Pav) and jatropha (Jatropha Curcas L.) leaves on Pseudomonas aeruginosa ATCC 27853. Methods: Anti-pseudomonas bacterial analysis was performed using the agar diffusion method with different concentrations of extracts in the range of 20-60% w/v. The MIC values of both extracts were determined using a microdilution method. Results: The results indicated that the P. crocatum leaves extract showed more potent inhibition than J. curcas extract. However, our findings demonstrated that bost extract can inhibit P. aeruginosa ATCC 27853 in the same MIC value (2.5-5%w/v). Conclusion: Although both extract has the same MIC values, but the P. crocatum extract provided higher diameter of inhibition and can be concluded to be the effective antipseudomonas natural drug.

Keywords: Piper crocatum Ruiz & Pav, Jatropha Curcas L, anti-pseudomonas, Pseudomonas aeruginosa ATCC 27853, comparison.