Abstract

A REVIEW ON MOUTH DISSOLVING TABLETS-A POTENTIAL DRUG DELIVERY SYSTEM

Parmar Manju, Gupta Ashish*, Sharma Ravi and Darwhekar Gajanan

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Abstract

Mouth dissolving tablet is one of the popular and widely excepted dosage form especially for pediatric patients, geriatric patient and few solid dosage form like capsule and tablet are fasting the problem like difficulty in swallowing (Dysphagia) resulting in many incidences of noncompliance and making the therapy in effective. Oral dosage form or oral route are most preferred route of administration for various drugs have limitation like first pass metabolism, Psychiatrics patient , Bedridden and uncooperative patient. FDTs formulation are designed to dissolve in saliva remarkably faster, within a few second (less than 60 sec), and content superdisintegrants to enhance disintegration rate of tablet in an oral cavity. This review depicts various technology with add of superdisintegrants; enhance bioavailability and solubility with fast onset of action then other oral and parenteral route of administration.

Keywords: Mouth dissolving, Super-Disintegrants, Dysphagia, Bioavailability.