Abstract

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF EPOXIDE DERIVATIVES

N. V. Sadgir*, Sunil L. Dhonnar and Shreya Shinde

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Abstract

Synthesis of epoxide involves two stages first chalcone synthesis followed by epoxide synthesis. The synthesized products were characterized by spectroscopic technique. This study explored the synthesis and antibacterial, antifungal activity of a series of epoxides. The synthesized epoxides were tested on E. coli, P. aeruginosa, and S. aureus, strains for antibacterial activity and against C. albicans, for antifungal activity. Compared to standard drugs, some of the synthesized compounds have moderate antibacterial activity.

Keywords: Chalcone, Epoxide, antibacterial, antifungal.