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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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ICV : 90.8

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Abstract

ATORVASTATIN INDUCED MYOPATHY: A CASE STUDY

Gouri S.*, Hannah Elizabeth Sabu, Dr. Chris Philip Mathew and Dr. Mohan Varghese

Abstract

Statins (HMG CoA Reductase inhibitors) are widely used for the treatment of hypercholesterolemia. They are also used in cardiovascular disease, stroke and are contraindicated in liver disease. Although statins are safe and well tolerated medications, they are known for muscle related adverse effects like myopathy. The definition of statin-induced myopathy is unexplained muscle pain or weakness accompanied by a creatine kinase (CK) concentration >10 times the upper limit of normal (ULN).

Keywords: Statins, HMG CoA Reductase inhibitors, hypercholesterolemia, myopathy.

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