Abstract

ANTI- BACILLARY DYSENTERY ACTIVITY COMPARING ON THE ETHANOLIC EXTRACT OF SUJI (DRACAENA ANGUSTIFOLIA ROXB.) AND SWEET POTATO (IPOMOEA BATATAS [L.] LAM) LEAVES

Sri Agung Fitri Kusuma* and Danni Ramdhani

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Abstract

Objective: In order to find potential anti-dysentery medication candidates, this study intends to assess the antibacterial activity of ethanol leaves extracts of sweet potato (Ipomoea batatas [L.] Lam) and suji (Dracaena angustifolia Roxb.) leaves against Shigella dysenteriae ATCC 13313. Methods: The study involved the collection and analysis of plant samples, extraction, moisture content assay, phytochemical screening, antibacterial activity using the agar-diffusion method and MIC testing using the macrodilution method against S. dysenteriae ATCC 13313. Results: The identified phytochemical compounds from both leaves extract were flavonoids, tannin, and polyphenolic compounds. With a same MIC range of 10–20% w/v, the both ethanol extract demonstrated a considerable zone of inhibition in a dose-dependent manner against S. dysenteriae ATCC 13313. Conclusion: The ratio of the suji leaf ethanol extract's comparative activity to the sweet potato leaf ethanol extract was 1:1.

Keywords: suji, Dracaena angustifolia Roxb., sweet potato, (Ipomoea batatas [L.] Lam), Shigella dysenteriae, comparison.