Abstract

RECONSTITUTABLE ORAL SUSPENSIONS (DRY SYRUPS): AN OVERVIEW

Casilda Bardeskar* and Rachel Geeverghese

Abstract

The advantages of oral dosage form that are responsible for its popularity are its ease of administration, patient compliance and stability of formulation. Dry syrups are the dry mixtures that require the addition of water at the time of dispensing. It is packed dry in bottles to preserve the stability of sensitive pharmaceutical ingredients. After reconstitution such formulations are to be administered in a specific period as indicated in the label claim of dry syrup packing. A number of commercial and official preparations are available as dry powder mixtures. Most of the drugs prepared as dry powders for oral suspension are antibiotics. The present review gives an account of the excipients used, methods of preparation of dry syrups along with the instruments used, their evaluations, ICH guidelines, the packaging materials used, examples of research articles, few marketed preparations and few of the patents obtained.

Keywords: Administration, patient compliance and stability of formulation.