Abstract

ANTI TOXIC EFFECT OF TANKANA AGAINST VATSANABHA-DRUG REVIEW

Dr. Sachin S. Rere*, Dr. Shital Mirajkar(Koparde), Dr. N. S. Gangasagre, Dr. Sachin B. Aghade

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Abstract

It is a not unusual place false impression a few of the public that Ayurvedic drug treatments are secure and without negative reaction. Many toxic flowers had been utilized in Ayurveda medicine. Aconiteprimarily based totally Ayurveda drug treatments are normally utilized by Ayurvedic physicians and conventional practitioners /people’s healers in number one healthcare. Aconite poisoning following use of natural treatments has been mentioned from Hong Kong, India and Nepal. According to toxicology, Vatsanabha (Aconitum ferox) is a cardiac poison. In Vatsanabha sever toxicity, cardiovascular capabilities include hypotension, sinus bradycardia, and ventricular arrhythmias. Treatment of poisoning in allopathy is particularly supportive. In Ayurveda in remedy of Vatsanabha toxicity Tanakan turned into advised as an antidote, however its mechanism now no longer known. So, a cautiously deliberate analytical examine turned into done for evaluation of Vatsanabha and Tankan to assess the antidote assets of Tankan. In this examine 4 samples [Ashuddha Vatsanabh (AV), Shuddha Vatsanabha (SV), Ashuddha Tankan with Ashuddha Vatsanabha (ATAV), Shuddha Tankan with Ashuddha Vatsanabha (STAV)] had been studied the usage of Thin Layer Chromatography (TLC). TLC plates had been visualised below 254 & 366nm. UV rays and spraying Dragandorff`s reagent & similarly Sodium Nitrite at the plates already sprayed with Dragandorff's reagent. The carried out examine suggests that Tankan delays and additionally reduces the poisonous consequences of Vatsanabha.

Keywords: Vatsanabha, Tankan, Aconite, Antidote. Thin layer chromatography.