Abstract

AN OVERVIEW: DEVELOPMENT AND CHARACTERIZATION OF HERBAL BASED LIPOSOMAL GEL FOR TREATMENT OF INFLAMMATION

Ajmal* and Sanjay Kuswaha

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Abstract

Recent years have seen a substantial increase in interest in the use of liposomal drug delivery systems for improving the bioavailability and therapeutic effectiveness of different pharmaceutical and cosmetic formulations. A unique herbal-based liposomal gel's development and characterisation as a possible medication delivery technology and skincare formulation are presented in this review study. The formulation of the liposomal gel uses lipid-based vesicles to enclose herbal extracts in order to safeguard the active ingredients, regulate medication release, and enhance skin penetration. The study starts out with a thorough analysis of liposomal gels and their benefits over traditional gel formulations. It emphasises the value of controlled release qualities and focused medication administration, which can result in better therapeutic results and less systemic adverse effects. The research next examines the liposomal gel's physicochemical assessment, looking at factors such particle size, zeta potential, pH, rheological characteristics, spreadability, and texture. To determine the formulation's long-term viability and shelf-life, stability studies are also carried out. The study also examines the effectiveness of encapsulating herbal extracts within liposomes, demonstrating the formulation's ability to maintain and safeguard the active ingredients during administration and storage. The results of this study show that the herbal-based liposomal gel performs better than traditional herbal gel formulations. The liposomal gel is a viable platform for delivering herbal constituents in medicines and cosmetic products due to its regulated and prolonged drug release, greater skin penetration, and increased bioavailability.

Keywords: Liposomal gel, Pharmaceuticals, Herbal, Skincare.