Abstract

SYNERGISTIC EFFECT OF AMLA, ORANGE AND STRAWBERRY EXTRACT ON IMMUNOMODULATOR ACTIVITY

S. Sureka*, S. Karpagam Kumara Sundari, K.A.S. Mohammed Shafeeq and R. Senthamarai 

Abstract

Immune system plays significant role in maintaining the health especially during pandemic situation. To strengthen the immune system there is a dire need of new safe, economical immunomodulator which is available to the common people. Currently fruits containing Vitamin C reported to possess immunomodulator activity due its free radical scavenging property. The aim of the research is to evaluate immunomodulator action of a group fresh fruit juices in vitro and in vivo. Fruits (Amla, Orange, Straw berry) were collected from local market, Trichy (Tamil Nadu) were screened for its Anti-oxidant activity by doing DPPH and H2O2 Test and confirming its immunomodulator action by determining the phagocytosis test, Collective Blood Cell Count, ESR and pH of blood. In vivo model includes Delayed Type Hypersentivity (DTH) response using suitable animal model described below.

Keywords: Fresh Fruit juices, in vitro phagocytic test, anti-oxidant activity using DPPH and H2O2 model and invivo evaluation of CBC, ESR and pH of blood samples.