Abstract

APPROPRIATENESS OF VANCOMYCIN USE AMONG RESIDENT DOCTORS IN EMERGENCY MEDICINE FOLLOWING AN EDUCATIONAL ACTIVITY

*Dr. Abdul Wahid Bhat MBBS, MD, MRCP, Dr. Mohd. Iqbal Mir, (MBBS), Basil Wahid Bhat (MBBS)

Abstract

Background: Drug utilization evaluation has an important role in controlling rational use of antibiotics to prevent the emergence of drug resistance. Methods: We conducted a prospective study in resident doctors about the appropriateness of vancomycin utility in patients presenting to emergency medicine at a tertiary care hospital. Data including patient's demographics, diagnosis, indication of vancomycin use, Dosage regimen, drug infusion rate and creatinine monitoring were reviewed on daily basis. Utility of vancomycin was analyzed about appropriateness before and fallowing an educational activity among the resident doctors. Results: 118 and 120 medical records were reviewed before and fallowing an educational activity on daily basis in this study. Empirical use of vancomycin was the most common and was found in 48(40.7%) patients fallowed by prophylactic in 43(36.4%) and specific in 8(39%). Creatinine monitoring was done in 50(42.4%), vancomycin infusion rate was adjusted in 86(72.9%) and vancomycin dose adjustment was found in 89(75.4%). Fallowing an educational activity, the vancomycin utility parameters were observed as empirical use in 78(60%), prophylactic in 40(38%), specific in one patient only. Creatinine monitoring was performed in 100(83%), regulation of drug infusion rate 120(100%) and dose adjustment in 120 (100%). Conclusions: The results revealed that vancomycin was commonly used empirically. lack of paying enough attention to the infusion rate and serum creatinine monitoring by resident doctors was observed. There was a significant increase in appropriate utilization fallowing an educational activity(p

Keywords: Vancomycin, Drug utilization, Appropriateness.