Abstract

PHARMACOLOGICAL STUDY OF SONANUM NIGRUM

Shivam Gupta*, Radhika Patel and Rajeev Shukla

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Abstract

The purpose of this article is to provide the most recent information for further exploitation and applications of S. nigrum in functional foods and medications. It does this by providing a thorough and systematic overview of the botanical, traditional uses, phytochemical compositions, pharmacological properties, clinical trials, and toxicity of S. nigrum. Originally from Southeast Asia, Solanum nigrum Linn. is a widespread edible medicinal herb that is now extensively dispersed in temperate to tropical regions of Europe, Asia, and America. Acute nephritis, urethritis, leucorrhea, sore throat, toothache, dermatitis, eczema, carbuncles, and furuncles are just a few of the conditions it has historically been used to treat. 188 chemical components from S. nigrum have so far been discovered. The main bioactive components of these are steroidal saponins, alkaloids, phenols, and polysaccharides. S. nigrum has been studied for its pharmacological properties, and these investigations have shown that it has a wide variety of therapeutic potential, including anticancer, anti-inflammatory, antioxidant, antibacterial, and neuroprotective effects both in vivo and in vitro.

Keywords: Solanum nigrum, saponins, alkaloids, phenols, anticancer, anti-inflammatory, antioxidant, antibacterial, and neuroprotective.