Abstract

QUALITY BY DESIGN (QBD) IN PHARMACEUTICAL FORMULATION DEVELOPMENT: A SYSTEMATIC REVIEW OF APPLICATIONS AND BENEFITS

Seema Devi*

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Abstract

Quality by Design (QbD) is a systematic approach to pharmaceutical formulation development that has gained prominence in recent years. It aims to ensure product quality by designing and controlling formulation and manufacturing processes rather than relying solely on end-product testing. This systematic review paper comprehensively explores the applications and benefits of QbD in the pharmaceutical industry. We analyze the key principles of QbD, its implementation across various drug formulations, and the resulting advantages, including improved product quality, reduced manufacturing costs, and enhanced regulatory compliance. Through this review, we highlight the significance of QbD in optimizing pharmaceutical development and fostering a culture of continuous improvement.

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