Abstract

AN OPEN LABELLED CONTROLLED CLINICAL TRIAL ON THE EFFECT OF BRAHMI AND PRANAYAMA IN PREMENSTRUAL DYSPHORIC DISORDER

*Dr. Tejashwini, Dr. Shrilatha Kamath and Dr. Arpana Radhesh

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Abstract

Objective: To compare the efficacy of Brahmi and Pranayama in Premenstrual dysphoric disorder. Methodology: An open labelled controlled clinical trial on the effect of Brahmi and Pranayama in Premenstrual dysphoric disorder. The study was conducted on 30 patients from OPD and IPD of Shri Dharmasthala Manjunatheshwara college of Ayurveda, Udupi. Patients fulling the diagnostic criteria of Premenstrual dysphoric disorder were only selected. Permuted block randomization was done and patients were allotted to two group. Each group had 15 patients. Group A Control group was advised to practice Nadi Shodhana Pranayama for 10 cycles and Brahmari Pranayama for 5mins every day at 7am on empty stomach for 60days. Group B Study group was advised to take Cap. Brahmi, 6 capsules on empty stomach only in the morning with warm water for 60 days. Cap. Brahmi were prepared in SDM pharmacy. Assessment was done 0th day, 30th, 60th day, 90th day and 120th day. Subjective and objective parameters were scored by standard method and were assessed before and after treatment on 0th day and on 60th day. All the parameters were analyzed statistically using paired t test for numerical data and Wilcoxon signed rank test for ordinal data comparing on 0th day and 60th day within the group. In between the group the numerical data was compared using unpaired t test and ordinal data was compared using Mann- Whitney U test. Result: Both the groups had statistical significance in most of the parameters. There is no statistically significant difference in between the groups except for Mood swing. Conclusion: Both the groups treated with Brahmi and Pranayama were efficient enough to reduce the symptoms of Premenstrual Dysphoric Disorder.

Keywords: Premenstrual Dysphoric disorder, Chittodvega, Brahmi, Pranayama.