Abstract

LITERARY REVIEW OF PHARMACOLOGICAL ACTIVITIES OF CISSUS QUADRANGULARIS L. W.S.R. TO ASTHISANDHANAKAR KARMA (BONE HEALING PROPERTY)

Dr. Sarita Sunil Bedarkar* and Dr. S. S. Shekokar

.

Abstract

Cissus quadrengularis L. or Asthishrunkhala is one of the most important plant in Ayurveda specially known for its bone fracture healing property. Since long ago Vaidyas have been using it for strengthening the bone. It is a common perennial climber, a succulent plant of family Vitaceae, also known as “Bone Setter” in English, or Hadjod in Hindi because of its ability to join bones and Asthisamhari, Kandvalli, Vajrangi in Sanskrit. In Ayurveda it is mentioned that this plant possesses many properties like Pachana (digestive aid), Sara (relieves constipation), Asthiyuk (strengthening bones), Vrishya (Aphrodisiac), Krumighna (destroys worms), Arshoghna (cures piles), Balya (provides strength), Amaghna, Kushthaghna (cures skin disorders). Cissus quadrangularis L. is fleshy, cactus-like climber widely used as a food item in India & is distributed throughout the tropical and subtropical regions. A variety of chemical constituents have been isolated and identified from Cissus extracts, including steroids, flavonoids, stilbenes, iridoids, triterpenes and Gallic acid derivatives. Recent Animal and in vitro studies have proved that it provides support in promoting bone fracture healing and as an anti-osteoporotic agent. The present paper is an attempt to highlight the studies in animals, humans and in vitro systems that have been conducted to determine the efficacy in promoting bone fracture healing and as an Antiosteoporotic.

Keywords: Cissus quadrangularis L, Pharmacological, Phytochemical, Asthisandhanakar karma, Bone healing property.