Abstract

CYCLOSPORINE: SEPSIS AND ACUTE KIDNEY INJURY

Harish Thanusubramanian, Bharti Chogtu* and Rahul Magazine

Abstract

A 60 year male with adult onset nephrotic syndrome with focal segmental glomerulosclerosis was on steroids for 4 months and cyclosporine for one month. He came with complains of cough and breathlessness. Chest x-ray showed middle right zone consolidation. He had anemia, leukocytosis and thrombocytopenia. His urea and creatinine levels were elevated at the time of admission. He was diagnosed of sepsis and was started on antibiotics. Cyclosporine was immediately withdrawn but corticosteroid was continued due to his primary condition. His urine output dropped and creatinine increased leading to acute kidney injury. It was diagnosed as cyclosporine induced sepsis leading to kidney injury. He was advised renal biopsy and hemodialysis for which he did not give his consent.

Keywords: acute kidney injury, cyclosporine, sepsis.