Abstract

GUAVA USED TO TREAT MOUTH ULCER

Vaibhavi Shirke*

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Abstract

The aim of this study was to formulate and evaluate an herbal gel from dried powdered guava leaves for the treatment of oral ulcers. The herbal gel was prepared using different concentrations of powdered guava leaves and propylene glycol Carbopol 934 as the gel base. The preparations were evaluated for various parameters. Infrared spectroscopy showed that there was no interaction between the ground guava leaves and the polymer. The prepared gel was transparent, homogeneous and the pH value varies between 7 and 7.5. The formulation showed acceptable rheological behaviour with adequate spreading and extrusion properties. Antifungal studies of the preparations have shown excellent efficacy against Aspargilious aureus, Candida albicans. Experimental evidence from invitational studies showed that powdered guava leaves contained flavonoids, so they had significant antioxidant activity. The developed herbal formula was stable, safe and effective compared to synthetic preparations for the treatment of mouth ulcers.

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