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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
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Abstract

GREEN FABRICATION OF SILVER NANOPARTICLES AND CHARACTERIZATIONWITHPLANTLEAFESSENTIALOIL COMPOUND GERANIOL AND THEIR ANTIFUNGAL ACTIVITY AGAINST HUMAN PATHOGENIC FUNGI

R. R. Thanighai Arassu, *Balwin Nambikkairaj and D. R. Ramya

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Abstract

A novel green approach for the synthesis and stabilization of silver nanoparticles (AgNPs) using plant leaf essential oil compound Geraniol under ambient conditions is reported in this article. The instant formation of AgNPs was analyzed by visual observation and UV–visible spectrophotometer. Further the effect of pH on the formation of AgNPs was alsostudied. The synthesized AgNPs were characterized by FT-IR, XRD, SEM with EDS, HR-TEM and fluorescence spectroscopy. Appearance of brownish orange colour confirmed the formation ofAgNPs. In the neutral pH, the stability of AgNPs was foundto be high. The stabilityof AgNPs is due to capping of phyto constituents present in the plant leafessential oil compound Geraniol which is evident from FT-IR studies. The XRD pattern of synthesized AgNPs showed their powder nature. HR-TEM studies revealed that the diameter of stable AgNPs was approximately29 nm. The antifungalactivityresultsshowed thatsynthesized silver nanoparticle from the plant leaf oil compound geraniol cas highly active against clinically isolated human fungal pathogens, Aspergillus niger, Aspergillus flavus, Candida albicans, Candidatropicalis and Candida kefyr.

Keywords: Aspergillusflavus, Greensynthesis, FTIR, HR-TEM, Silvernanoparticles.


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