Abstract

A CLINICAL STUDY TO EVALUATE THE EFFECT OF NITYA VIRECHANA IN AMAVATA W.S.R RHEUMATOID ARTHRITIS

Dr. Sangamesh Patil*, Dr. Manjunath Kanthi and Dr. Niranjan Rao

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Abstract

Background: Amavata is a disease characterized by the involvement of morbid vata, pitta, kapha dosha and Ama. When a person endowed with Mandagni & if indulges in the specific etiological factors such as Virudda ahara, Cheshta etc leads to the formation of ama which gets provoked by morbid Vatadosha and mobilized to different Kaphasthanas resulting in the formation of Amavata.[1] Amavata mimics Rheumatoid arthritis in modern parlance. The worldwide prevalence of this disease is approximately 0.8% (0.3% to 2.1%) of the population. In India the prevalence of Rheumatoid Arthritis is 0.5% to 0.75%.[2] Virechana is one amongst the Samshodhana karma, mentioned in classics which removes the morbid doshas through Adhomarga of shareera.[3] Nitya virechana karma is one such treatment selected for Amavata it helps in nirharana of vitiated dosha, ama and purana mala.[4] Objective: To evaluate the efficacy of Nitya Virechana with Gandharva Hastadi Erandataila[5,6] in patients suffering from Amavata (Rheumatoid Arthritis) as per guidelines of classical text books. Design: It is a Single blind clinical study with pre- test and post-test design, carried out in S.D.M. Ayurveda Hospital, Udupi. Study Selection: A single group consisting of 20 Patients diagnosed as Amavata, according to the diagnostic criteria having either gender selected for the study. Intervention: After selecting a patient diagnosed with Rheumatoid Arthritis based on selection criteria, individual is given Nitya virechana for 7 days. Nitya Virechana on day 1 to day 7 - The subject is administered with Gandharva hastadi Earandataila in empty stomach, in a dose of 25 ml in morning followed with shunti kashaya as anupana. Day 1st and 7th day comparison is done. Amavata lakshanas and inflammatory markers like-CRP, RA, ESR and ASLO are assessed. Result: Nitya Virechana karma shown extremely significant changes in the symptoms like pain, redness, swelling, warmth, tenderness, range of movement, Angamarda, Aruchi, Alasya, Gouravata, Sandhishula, Sandhishotha, Agnimandhya, Utsahani, and Nidraviparyaya and also significant changes noted in inflammatory markers.

Keywords: Amavata; Rheumatoid Arthritis; Nitya Virechana; Gandharva hastadi eranda taila.