Abstract

STANDARDIZATION OF YAVAKSHARA CHURNA AND MADHU ON SCALING WOUND- A DRUG REVIEW

Dr. Mridulata Maurya*, Prof. B. Mukhopadhyay and Prof. Rajesh Bansal

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Abstract

Periodontal tissue is destroyed by the irritants of dental tartar deposits.[1] Therefore, all the dental tartar must be removed by ultrasonic scaler first. After that, Yavakshara churna (an alkali preparation from the plant Hordeolum barley) and Madhu (honey) paste are applied on the scaling wound described by Acharya Vagbhat.[2] Prior to oro-dental application, Yavakshara churna and Madhu should be standardized by using modern parameters such as pharmacognostic evaluation, chemical analysis, powder microscopy, and sophisticated instrumental analysis. Scanning electron microscopy (SEM) analysis was done to see the morphology of Yavakshara churna. The heavy metals are toxic to our bodies and pesticide residues in plants are retained for a long-time causing side-effect in the body. The microbiological test was done to see the contaminations/affections if any, and the mycotoxin test to see the presence of aflatoxin if any. After analysis with modern parameters, it was found that all the parameters of both drugs are within the permissible limit as per API. The heavy metals were seen within the permissible limits as per API; pesticide residues were seen within the permissible limits as per API; microbiological parameters were seen within the permissible limit as per API, and mycotoxins were seen within the permissible limits as per API in both drugs Yavakshara churna and Madhu. Additionally, the negligible toxicity profile of both drugs indicates that they may be used in herbal paste on the scaling wound in the future.

Keywords: Standardization, Yavakshara churna, Madhu, Scaling wound, Drug review.