Abstract

GREEN SYNTHESIS OF SILVER NANOPARTICLES AND CHARACTERIZATION USING PLANT LEAF ESSENTIAL OIL ROSEMARINUS OFFICINALIS AND THEIR ANTI FUNGAL ACTIVITY AGAINST HUMAN PATHOGENIC FUNGI

R. R. Thanighai Arassu, Balwin Nambikkairaj* and D. R. Ramya

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Abstract

Present study, we utilized the bio–reductive potential of the plant leaf essential oil Rosemarinus officinalis, for the synthesis of silvernanoparticles (AgNPs). Thegreen synthesized AgNPs was achievedat 80°C and found to be highlystablein roomtemperature for some time. The Ag NP swasfoundto besmall dotround in shape with an averagesize of ~52 nmindiameter. The AgNPs were characterize dusing ultraviolet-visible absorption spectroscopy fourier transform Infrared spectroscopy (FTIR), transmission electron microscopy (TEM), Scanning electronmicroscopy and Edx (SEM). The anti-fungal activities of the synthesized AgNPs were tested against a few human fungal pathogens Aspergillus niger, Aspergillus flavus, Candidaalbicans, Candida tropicalis and Candida kefyrshowed high activity againstthese microorganisms. The results showed that thesize and the shape canbe easily controlled by employing the optimum concentrations ratio of AgNO3 solution and also varying temperature and incubation time. Thesynthesized AgNPs from Rosemarinus officinalis plantleaf oil can be used as a potent therapeutic agentand for anti-canceractivity.

Keywords: Aspergillus niger, Green synthesis, XRD, Silver nanoparticles, Tem.