Abstract

PHYTOCHEMICAL SCREENING AND ANTIMICROBIAL STUDIES OF STROBILANTHES CONSANGUINEUS (NEES) CLARKE

A. Renjith Alex*, Annu Gigi, Dona Merin Sunny, Femina Sulaiman and Neenu M.

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Abstract

The aim of the present study was to investigate the antimicrobial and preliminary phytochemical properties of Strobilanthes Consanguineus (Nees) Clarke. The organic solvents (Petroleum ether, Chloroform and Methanol) and aqueous extracts from the leaf of Strobilanthes Consanguineus (Nees) Clarke (Acanthaceae) were tested against Salmonella typhi, Klebsiella pneumonia, E. coli, Staphylococcus aureus and Candida albicans by agar well diffusion method. In antibacterial activity, Chloroform and methanol extracts show marked activity and zone of inhibition were closest value to the standard drug (Ciprofloxacin) than the aqueous extract. The methanolic extract showed good activity of antifungal screening and zone of inhibition is closest value to the standard drug (Ketoconazole). Preliminary phytochemical analysis of extracts revealed the presence of phytochemicals such as alkaloids, tannins, carbohydrates, phenolic compounds, steroids, phytosterols, flavonoids, saponins, fats and fixed oils. The result of this study validates to the isolation of antibacterial agents from the leaf extracts of Strobilanthes Consanguineus (Nees) Clarke.

Keywords: Strobilanthes Consanguineus (Nees) Clarke, Phytochemical analysis, Antimicrobial activity, well diffusion method.