Abstract

EXPLORING THE POTENTIAL ANTI-DIABETIC PHYTOCONSTITUENTS OF PORTULACA OLERACEA L: AN INSILICO STUDY

Yenumala Vamshidhar Reddy*

.

Abstract

‘Portulaca oleracea L’ is commonly known as purslane, because of to its nutritional and medicinal advantages. It has important anti-diabetic ability and it is a rich source of vitamins, minerals and various healthbeneficial Secondary Metabolites like Flavonoids and Terpenoids. The Insilco study may be significant for developing potent anti-diabetic medications from this plant. The goal of the current study was to employ an in-silico method to determine the best bioactive components of Portulaca oleracea L as potential therapeutic agents against Diabetes mellitus. Phytoconstituents were obtained and docked to a targeted Protein. Finally, six Phytoconstituents - Isoharmnetin, Kaempferol, Luteolin, Apigenin, Portulene, and Genistein were chosen because they effectively bind to the targeted Protein active binding site. According to the research, Portulaca oleracea L screened Phytoconstituents can be exploited as potential therapeutic medication candidates to treat diabetes mellitus.

Keywords: Portulaca oleracea L, Phytoconstituents, Molecular Docking, Anti-Diabetic agent, Insilico Study.