Abstract

EXTRACTION, CHARACTERIZATION AND FUNCTIONALIZATION OF TAMARIND KERNEL POWDER- A NOVEL PHARMACEUTICAL EXCEPIENT

R. Sailaja*, Jagadeeshpanda, B. Kalajyotsna, B. Hanumanth, Ch. Bhargavi, S. Rahitya Sri and T. Siddarth

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Abstract

The objective of this study was to extract and further characterize the tamarind kernel powder (TKP) obtained from Tamarindus indica as an excipient and explores its pharmaceutical applications. The tamarind seeds were kept in hot air oven at 50oc for half an hour. The outer seed coat was removed and the kernels were grounded to fine powder. The obtained powder was sieved through suitable sieves. The powder was analyzed by FTIR. The Pre-formulation studies were conducted for dried Tamarind kernel powder. The floating nature and Super disintegrant activity were studied by preparing dummy tablets. The Mucoadhesive strength was measured by Modified physical balance method by using goat mucosa. The work has concluded that Tamarind kernel powder is an emergent excepient and can be used as super disintegrant, polymer in sustained and controlled drug delivery and as a bioadhesive polymer.

Keywords: Tamarind kernel pwder, Muco adhesive, Super disintegrant, Modified physical balance method, Floating lag time and Disintegration time etc.