Abstract

FORMULATION AND EVALUATION OF ACECLOFENAC EFFERVESCENT GRANULES

Subhashitha S.* Nikhil H. Y., Pallavi Nayak, Shwetha Nayak and Sri Lakshmi Prasida, Swasthi and Ravi Kumar Naik

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Abstract

The aim of this study is to develop and physicochemically evaluate the effervescence granules of aceclofenac. In this study we adopted salt formation technique to enhance the drug and also we can get other advantages like better patient compliance and avoid the first pass effect. In this study the aceclofenac effervescent granules were prepared with different excipients in five formulation and evaluated each for effervescent test and pre compressibility parameters. Here aceclofenac is used which shows anti-inflammatory drug release rate.

Keywords: Effervescent granules, Aceclofenac, dissolution study, salting form, release rate, granules.