Abstract

FORMULATION AND EVALUATION OF HARIDRADI VARTI EXTRACTS FOR ITS IN-VITRO ANTIBACTERIAL ACTIVITY

Dr. Ankita Prajapati* and Dr. Surekha S. Medikeri

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Abstract

Local treatment explained as Netra Kriyakalpa plays a crucial role for the treatment of eye diseases. Netravarti which is applied as Anjana belongs to one of the Netra Kriyakalpa. Haridradi varti is a preparation indicated in all eye diseases explained in Chakradatta which contains Haridra, Daruharidra, Haritaki, Vibhitaki, Amalaki, Lodhra, Yashtimadhu and Raktachandana. Extraction procedures play a crucial role in obtaining the therapeutic benefits of crude drugs, ensuring the purity and concentration of active compounds in lesser dose, and facilitating the development of various medicinal products for effective and controlled administration. Abhishyanda is classified under Sarvagata Netraroga which affects eye in all ways and is said to be the cause of all the eye diseases, which can be compared to Conjunctivitis based on its signs and symptoms. The primary base for treating bacterial infections is reliant on the use of Antibiotics. Due to inappropriate use of antibiotics, which can lead to bacterial adaptation or mutations, in turn growth of new strains of bacteria that can give rise to antibiotic resistance. Hence, there is a need to develop a new antimicrobial agent based on targeted drug delivery. Haridradi varti extracts is chosen in the present study focusing on its antibacterial effect in-vitro, against gram -ve and gram +ve bacteria by assessment of zone of inhibition and minimum inhibitory concentration using OD method. The results showed promising antibacterial activity in the lowest concentration of Haridtadi varti extracts.

Keywords: Haridradi varti, Haridradi varti extract, Antibacterial, Phytochemicals, Bacteria.