Abstract

AN OVERVIEW ON NANOEMULSION: A NOVEL DRUG DELIVERY SYSTEM

Sayali S. Patil* and Dr. Sachin A. Nitave

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Abstract

In order to address the major issues with traditional medication administration techniques, a contemporary approach to drug administration has been created. Due to the unique characteristics of nanoscale emulsions, such as their outstanding stability, appealing look, excellent performance, and sensory benefit, interest in them has significantly increased in recent years. To improve the transport of pharmacologically active compounds, nanoemulsions are emulsions made in nanoscale diameters. Nanoemulsion typically has droplet sizes between 20 and 200 nm. The dimension and form of the particles scattered in the continuous phase is the primary distinction between an emulsion and a nanoemulsion. A full overview of a nanoemulsion system is provided by this review. These are the isotropic systems that are thermodynamically stable when two immiscible liquids are combined into one phase using an emulsifying agent like a surfactant and a co-surfactant. The focus of this paper is on presenting a broad grasp of the formulation of nanoemulsions, the preparation process, characterisation techniques, assessment criteria, and a variety of applications. Additionally, the chemical and thermodynamic durability, longevity, dispersibility, viscosity, friction, friccohesity, refractive index, % transmittance, pH, and osmolarity of nanoemulsions are examined.

Keywords: Nanoemulsion, emulsion, microfluidization, High-pressure homogenization, Ultrasonication, emulsifying agent.